Tags: Sunburn

Sunburn is an acute inflammatory response to overexposure to ultraviolet B (UVB) radiation, leading to direct DNA damage, apoptosis of keratinocytes, and immune cell activation. Clinically, it presents as erythema, pain, swelling, and in severe cases, blistering. UVB radiation causes the formation of cyclobutane pyrimidine dimers (CPDs), which trigger inflammation and immune suppression. Additionally, UVA […]